To see the effectiveness of preoperatively administered furosemide for preventing hypoosmolality and hyponatremia during TURP, 30 patients undergoing TURP were followed every preoperatively, 30 min intraoperatively as well as immediate
postoperatively 6
hours and 24 hours postoperatively with measurement of serum sodium serum potassium and serum osomolality. Among the 30 patients, 15 patients (experimental group) were administered furosemide immediately before TURP, the other 15 patients
(control
group) were not administered. We compared the changes of serum sodium, serum potassium and osmolality of experimental group with those of control group. The result showed that the serum sodium and osmolality were decreased significantly (p<0.01)
in
control group, but wee not decreased significantly in experimental group. Thus, the preoperatively administered furosemide may prevent the dilutional hyponatremia and hypoosmolality during TURP, and may be helpful in high risk patient such as
congestive
heart failure and poor renal function.
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